Fig. 3: Relationship between blood transcript levels of MX1 and IFI27 with symptoms and viral load by time from SARS-CoV-2 challenge. | Nature Communications

Fig. 3: Relationship between blood transcript levels of MX1 and IFI27 with symptoms and viral load by time from SARS-CoV-2 challenge.

From: SARS-CoV-2 human challenge reveals biomarkers that discriminate early and late phases of respiratory viral infections

Fig. 3

Individual standardised blood transcript levels of MX1 and IFI27 against (A) symptom scores and (B) nose and throat viral loads in participants who developed replicative virus infection (N = 17), stratified by time after virus challenge, with dashed line to represent the threshold (Z > 2) for elevated transcript levels. C Individual standardised blood transcript levels of MX1 and IFI27 (connected data points, left axis) and loess smoothed summary for nose viral load (black line ± 95% CI, right axis) in participants who developed replicative virus infection (N = 17), by time from virus detection in nose swabs > 4 Log10 copies/mL.

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