Fig. 2: Linear predictor for the fit of the Log2-based DF50. | Nature Communications

Fig. 2: Linear predictor for the fit of the Log2-based DF50.

From: Early assessment of antibodies decline in Chagas patients following treatment using a serological multiplex immunoassay

Fig. 2

The Log2DF50 was modelled with a longitudinal random intercept nested Linear Mixed Model, against time, treatment and the interaction of time and treatment, taking into account 2 (baseline and 6 months) or 3 (baseline, 6 and 12 months) timepoints, nesting 15 antigens per patient, and 30 patients in each of 7 treatment subgroups. Nested models keep the connection between the patient and the antigens. a At 6 months, and (b) At 12 months after the start of treatment. Log2 Binary logarithm, DF50 Dilution Factor 50 at which 50% of the original reactivity remains, BZN Benznidazole.

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