Fig. 3: Multimodal region-to-region correlations.

a–c Functional connectivity matrices showcasing correlations between each pair of regions defined based on the Allen common coordinate framework (CCF). The upper triangles show region-to-region correlation (RRC) values derived from the blood oxygen level-dependent (BOLD) data. Lower triangles depict the corresponding RRC values for oxygenated (HbO), deoxygenated (HbR), and total (HbT) hemoglobin. d–f Map of the RRC values (r > 0.1) obtained from BOLD versus functional optoacoustic (fOA)-derived components for connection edges, accompanied by the statistical distribution of the RRC values. Gray solid lines depict the linear fit. Mo = motor areas; SSp = primary somatosensory areas; SSs = supplementary somatosensory areas; Gu = gustatory areas; Visc = visceral areas; Aud = auditory areas; Vis = visual areas; Por = postrhinal areas; Cg = anterior cingulate areas; Lim = limbic areas; Orb = orbital areas; Rs = retrosplenial areas; Ptl = parietal areas.