Fig. 4: Recent directional selection in Indonesian Papua (N = 104) isolates. | Nature Communications

Fig. 4: Recent directional selection in Indonesian Papua (N = 104) isolates.

From: Genomic analysis of global Plasmodium vivax populations reveals insights into the evolution of drug resistance

Fig. 4

Manhattan plots showing integrated haplotype homozygosity scores (iHS) for SNPs in a pre-2014 isolates (N = 75), b post-2014 isolates (N = 29), d 2008–2009 isolates (N = 18), e 2016–2017 isolates (N = 10), and the cross-population test, Rsb, showing SNPs under differential selection between c pre-2014 vs. post-2014 isolates and f 2008–2009 vs. 2016–2017 isolates. Loci in critical regions, defined here as SNPs with an iHS score of P < 1 × 10−4 or Rsb score of P < 1 × 10−5 (two-sided tests), are highlighted in blue (iHS) and red (Rsb).

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