Fig. 7: pTRC have distinct trajectories in responder tumors. | Nature Communications

Fig. 7: pTRC have distinct trajectories in responder tumors.

From: A minimal gene set characterizes TIL specific for diverse tumor antigens across different cancer types

Fig. 7

A UMAP projection of the expression profiles of 45,022 pTRC from pTRC colored by clusters. B Relative expression of top 5 most differentially expressed genes in each cluster. C Boxplot of proportion of C1 and C5 pTRC in responding (n = 6) and non-responding tumors (n = 9), the comparison was performed using two-sided Wilcoxon rank-sum test. D Single patient RNA velocity visualized on the UMAP. E, F Differentially expressed genes between C1 and C5 (E) as well as C1 and C4 (F).

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