Fig. 3: Off-on-off” mechanism of ND and cycle response evaluation of NDPs. | Nature Communications

Fig. 3: Off-on-off” mechanism of ND and cycle response evaluation of NDPs.

From: NIR-II-excited off-on-off fluorescent nanoprobes for sensitive molecular imaging in vivo

Fig. 3

a Partial 1H NMR spectra monitoring of ND in the presence of NaHS and NaClO (1.2 equiv) in THF-D8/water (v/v = 95/5). b Schematic illustration of the “off-on-off” NIR-II fluorescence evaluation of NDPs (5 μg mL−1) in vitro. Created in BioRender. Jiajing, G. (2022) BioRender.com/m53h190. c Quantified NIR-II fluorescence intensity of (b) (n = 3 independent samples; mean ± SD). d Schematic illustration of the “off-on-off” NIR-II fluorescence evaluation of NDPs in mice. e In vivo NIR-II fluorescence images of NDPs (2 μg mL−1, 10 μL) upon different treatments, n = 3 mice per group.

Back to article page