Fig. 3: Signaling between fibroblasts and epithelial cells contributes to engraftment. | Nature Communications

Fig. 3: Signaling between fibroblasts and epithelial cells contributes to engraftment.

From: Molecular correlates for HPV-negative head and neck cancer engraftment prognosticate patient outcomes

Fig. 3

A Schematic of the strategy used to classify proteins as epithelial- or fibroblast-derived. B The log2(E/N) fold changes for epithelial- or fibroblast-assigned proteins P-value is from a two-sided Wilcoxon rank-sum test (n = 347 epithelial, 97 fibroblast). C UpSet plot depicting the overlap between proteins in the CCI interaction database that could be assigned a cell type, and were increased in engrafters. D Circos plot depicting the putative interactions between engraftment-associated proteins which could be assigned as epithelial- or fibroblast-derived. Boxplots show the median, interquartile ranges, and 1.5x IQR. Source data are provided as a Source Data file.

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