Fig. 1: Comprehensive transcriptional profiling of cell types across the mouse CN.
From: Molecular logic for cellular specializations that initiate the auditory parallel processing pathways
a Anatomy of mouse cochlear nucleus (CN; Light blue: VCN. Dark blue: DCN) and depiction of neuronal cell types (cartoon drawings) across the CN (sagittal view), colored by cell type identity. D dorsal, P posterior, M medial. The 3D brain model was generated with Brainrender (Ver. 2.1.10). b UMAP visualization of 31,639 nuclei from CN neurons clustered by over-dispersed genes, colored by cluster identity. Each cluster labeled by key marker genes. c Right: dendrogram indicating hierarchical relationships between clusters. Left: dot plot of scaled expression of selected marker genes for each cluster shown in (b); see Supplementary Data 1. Circle size depicts percentage of cells in the cluster in which the marker was detected (≥1 UMI), and color depicts the normalized average transcript count in expressing cells. See Figs. S1–3 for more technical details and annotations.
