Fig. 3: Genetic overlap between EUR ancestry male and female participants, using MiXeR. | Nature Communications

Fig. 3: Genetic overlap between EUR ancestry male and female participants, using MiXeR.

From: Multi-ancestry meta-analysis of genome-wide association studies discovers 67 new loci associated with chronic back pain

Fig. 3

Venn diagram reports numbers in thousands of variant risk loci (standard error) related to the first trait (gray circle), second trait (orange), and the mutually shared variants (gray overlap). Genetic correlation is depicted as a number and red progress bar. The two center plots show conditional QQ plots of trait 1 on subset 2 and trait 2 on subset 1. The model log-likelihoods based on the number of causal variants are shown in the rightmost plot. The solid blue line reflects the average likelihood across the 20 MiXeR runs. The dotted blue line reflect the likelihood of individual runs.

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