Fig. 4: Scope of cross-coupling partners.

Conditions: Rac-1 (0.05 mmol), 2 (0.10 mmol), Pd₂dba₃ (5 mol%, 0.0025 mmol), ligand (12 mol%, 0.0060 mmol) and CsF (0.10 mmol) in THF/H₂O (v/v = 9/1, 0.5 mL) stirred at 30 °C. ^aThe reaction was conducted at 40 °C.