Fig. 5: Crystal structure of the Primase-Rpa2WH complex.
From: Communication between DNA polymerases and Replication Protein A within the archaeal replisome
a–c Electron density map and model of the Primase-Rpa2WH complex crystal structure. The 2mFo-DFc electron density map is contoured at σ = 1.5. c PriS-Rpa2WH interface, with Rpa2WH residues colored according to the intensity ratio Icplx/Ifree from blue (weak attenuation) to red (large attenuation) as in Fig. 3k. d–e Detailed view of the interface between PriS and Rpa2WH. f Surface of Primase and Rpa2WH colored according to their Coulomb potential, calculated in ChimeraX v1.784; and multiple sequence alignment of the linker between the trimeric core helix of Rpa2 and the WH domain in Thermococcales showing the conservation of acidic residues.
