Fig. 1: Measurement of NA duplex stability by MT experiments.
From: Counterintuitive DNA destabilization by monovalent salt at high concentrations due to overcharging
Source are provided as a Source Data file. a Manipulation of NA hairpin using magnetic tweezers. b The NA hairpin is unfolded by the external force. c Illustration of the construct of three types of NA hairpins. Black for DNA bases and blue for RNA bases. d The unfolding and folding of an NA hairpin are indicated by abrupt changes in DNA extension during stretching and relaxing, respectively. e At the transition force \({f}^{*}\), the NA hairpin hops between the folded and stretched states with equal probability. f The free energy difference between the folded and unfolded hairpin. g Transition force as a function of salt concentration. The averages and standard errors from several molecules (four for CsCl and three for other ions) are plotted as data points and error bars.
