Fig. 4: Validation of TSMs using two validation datasets.
From: Universal, untargeted detection of bacteria in tissues using metabolomics workflows
Area under the curves (AUCs) were determined for each variable where there were at least 3 bacterial profiles/observations in each dataset. a Boxplots showing AUCs for each taxon, with overlaid data points, for internal (n = 263 TSM) and external (n = 134 TSM) datasets. Box limits show the 25th and 75th percentiles, with the median marked in black. No order-level TSMs could be tested in the external dataset, and only one at the genus-level. Histograms of AUCs for b internal and c external datasets, spanning the range 0.4−1.0 in intervals of 0.05. The median values (and interquartile ranges) for internal and external markers are 0.997 (IQR 0.047) and 0.985 (IQR 0.071). IQR: interquartile range. Source data are provided as a Source Data file.
