Fig. 2: Synthesis of intermediates and target probes.

A Synthesis route of compounds 6 and 9. B Synthesis route of NIR-I CL probes (CL-O1 and CL-O2). C Synthesis route of NIR-II CL probes (CL-O3, CL-S3, and CL-Se3).
A Synthesis route of compounds 6 and 9. B Synthesis route of NIR-I CL probes (CL-O1 and CL-O2). C Synthesis route of NIR-II CL probes (CL-O3, CL-S3, and CL-Se3).