Fig. 2: Programmable communication mechanisms of DR-AMCN.

a Diagram of basic communication mechanisms, including one-to-one, one-to-many, and many-to-many communication. b–f Schematic, representative AFM images and product statistics of the communication, including directional communication between nodes N 0 and N 1. Sample size is 112, with 104 for P 01. b orthogonal communication between nodes N 0, N 4 and nodes N 1, N 2 generating path 0 → 1 (blue) and 4 → 2 (red). Sample size is 111, with 52 for P 01 and 51 for P 42. c, d parallel communication between node N 0 with N 1 or N 2 generating path 0 → 1 (blue) and 0 → 2 (red) without bias. Sample size is 224, with 58 for P 01 and 57 for P 02. e as well as multiplexed communication for path 0 → 1 (blue), 0 → 2 (red), 4 → 1 (golden), and 4 → 2 (purple) through a common connector. Sample size is 136, with 31 for P 01, 30 for P 02, 32 for P 41 and 34 for P 42. f The x in the product statistics represents deserted reactants and other side products. The yield of each path was calculated by counting the number of target DNA nanostructures over all nanostructures. Three AFM images were counted for each DNA nanostructure, and each image was from an independent experiment. Source data are provided as a Source Data file. Scale bars, 50 nm.