Fig. 2: Synthesis and characterization of 4 kinds of hypoxia-tolerant polymeric photosensitizer (P1-P4).
From: Hypoxia-tolerant polymeric photosensitizer prodrug for cancer photo-immunotherapy
a Chemical structure of P1-P4. b UV-Vis absorption and c Fluorescence spectra of F127 coated P1-P4 (PN1-PN4) in H2O, arb. units, arbitrary units. Generation of d 1O2, e O2•- and f •OH determined by fold changes of fluorescence intensity of SOSG, DHR123 and HPF in NP1-NP4 ([BTP-OD] = 5 μg/mL) solution after NIR irradiation (808 nm, 0.2 W/cm2) for different time (n = 3 independent experiments). g Molecular energy level of P1-P4 using cyclic voltammetry (0.1 mol L−1 Bu4NPF6 dichlorobenzene/ac etonitrile solutions at a scan rate of 50 mVs−1). h Mechanism of Type-I PDT. The mean values and SD are presented. Source data are provided as a Source Data file.
