Table 3 Differentially expressed genes after 6 h of AVX420 treatment

From: Next generation thiazolyl ketone inhibitors of cytosolic phospholipase A2 α for targeted cancer therapy

Gene name

log2FC

Adjusted p-value

CHAC1

2.25

8.12E-38

L3MBTL2-AS1

2.13

8.90E-05

SESN2

1.59

3.07E-28

SLC7A11

1.57

9.03E-06

ADM2

1.49

1.65E-10

ENSG00000260498

1.44

6.37E-03

LINC-PINT

1.34

2.15E-11

VLDLR

1.27

3.68E-10

SLC6A9

1.25

2.93E-06

GPT2

1.24

3.60E-05

ULBP1

1.2

5.06E-04

DDIT3

1.15

1.13E-18

LY9

1.05

1.81E-03

ATF3

1.05

2.20E-08

YAP1

1.04

9.19E-04

VLDLR-AS1

1.02

5.37E-05

  1. Differential expression analysis using a P-value cut-off of <0.01 (after multiple testing adjustments), and a log2 fold change (log2FC) > 1 or <−1.