Fig. 2: Manhattan plots of GWAS for FPCs 1-6.
From: Multi-omic spatial effects on high-resolution AI-derived retinal thickness
For each FPC 1-6 (A–F), Manhattan plots (right) summarising the GWAS results, with each point representing a SNP, ordered by chromosome and position (x-axis). The y-axis indicates the -log10 p-value (p-values based on a two-sided t-test, for the SNP beta in the linear regression). To the left, FPC representations are shown as the Pearson correlation coefficent between individual FPC scores and each pixel-wise RT value.
