Fig. 4: High-resolution cryo-EM structure of the TPP riboswitch.
From: Scaffold-enabled high-resolution cryo-EM structure determination of RNA
A The unsharpened cryo-EM map as well as the corresponding model are shown for the scaffolded TPP riboswitch. The density and model is colored to match the secondary structure in Fig. 3A. B The high-resolution density surrounding the thiamine pyrophosphate binding site allowed for the precise characterization of ligand binding by the riboswitch. The model overlaid with density is shown below.
