Fig. 5: Stereoselective synthesis of 1,n-diols bearing two stereogenic centers.
From: A modular approach to catalytic stereoselective synthesis of chiral 1,2-diols and 1,3-diols
aNiBr2.DME (10 mol%), dtbbpy L7 (15 mol%), TBADT (2 mol%), K3PO4 (0.24 mmol) in MeCN (1 mL) under the irradiation of LEDs (10 W, 390 nm) at 25 oC. bNiBr2.DME (10 mol%), L4 (15 mol%), TBADT (5 mol%), K3PO4 (0.30 mmol) in acetone (0.5 mL) and PhCF3 (0.5 mL) under the irradiation of LEDs (10 W, 390 nm) at 25 °C. cL6 was used as the ligand instead of L4. The diastereomeric ratios (d.r.) were determined by 1H NMR analysis.
