Fig. 2: SOT recipients have higher SARS-CoV-2 viral rpM and impaired viral clearance compared to controls. | Nature Communications

Fig. 2: SOT recipients have higher SARS-CoV-2 viral rpM and impaired viral clearance compared to controls.

From: Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients

Fig. 2

a, b Box plots showing SARS-CoV-2 viral reads per million (rpM) at Visit 1 of a transplant (yellow, n = 86) and control groups (blue, n = 172), and b different organ transplant types (heart—n = 10, kidney—n = 41, liver—n = 14, lung—n = 17). P values were calculated with a a linear model or b two-sided likelihood ratio test. Boxes show the median and interquartile range (IQR), whiskers were calculated as the 25th percentile minus 1.5 times the IQR and the 75th percentile plus 1.5 times the IQR. c Plot showing the dynamics of viral rpM up to 30 days after hospital admission of the transplant and control groups. The blue and orange lines indicated the generalized additive mixed model fits, and the ribbons indicated the 95% confidence interval of the fits. P value was calculated for the interaction between SOT status and days from admission with a generalized additive mixed model. The number of patients sampled at each time point is depicted graphically below the X axis of (c).

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