Fig. 3: mosGILT antibodies decrease P. falciparum and P. berghei oocyst cross-sectional area.

Cross-sectional area (size) of oocysts from mosquitoes that took a Plasmodium falciparum (a, Pf) or Plasmodium berghei (b, Pb, p = 0.0308) infected blood meal from a membrane feeder with mosGILT (a, n = 123; b, n = 60) or control (a, n = 200; b, n = 65) antibodies. Oocysts were imaged seven days post-infectious blood meal. Cross-sectional area was measured using ImageJ. Each dot represents the cross-sectional area of an individual oocyst. The blue and red horizontal lines indicate the medians for the control and intervention groups, respectively. The thin lines indicate upper and lower quartiles. P. falciparum and P. berghei experiments were replicated a total of three times. Two-Tailed Mann-Whitney was used to determine the significance of oocyst abundance (*p ≤ 0.05, ****p ≤ 0.0001). Source data are provided as a Source Data file.