Fig. 1: Normalization of increased areal bone mineral density (aBMD) assessed by dual-energy X-ray absorptiometry (DXA) in myelofibrosis after allogeneic hematopoietic stem cell transplantation (allo-HSCT).

a Representative DXA-derived images of the lumbar spine and left hip before (Pre-HSCT) and 1 year after allo-HSCT (Post-HSCT). b Spinal aBMD of myelofibrosis patients before allo-HSCT (Pre, n = 66) and after allo-HSCT (Post, n = 30), along with the control group (Ctrl, n = 66). On the right, only patients with individual courses (connected by lines, n = 14) are shown. c Femoral aBMD of the three groups (Pre, n = 66; Post, n = 30; Ctrl, n = 66) and individual patient courses (n = 14). d Spinal T-score of the three groups (Pre, n = 66; Post, n = 30; Ctrl, n = 66) and individual patient courses (n = 14). e Spinal T-score of the three groups (Pre, n = 66; Post, n = 30; Ctrl, n = 66) and individual patient courses (n = 14). The median (center line, 50th percentile) and interquartile range (box edges, 25th to 75th percentile) with whiskers extending to the minimum and maximum values are depicted. Each data point is shown. Differences between the three groups were calculated using Kruskal-Wallis H test with Dunn’s test (b–e). Differences for the individual courses of patients (Pre and Post, connected points) were calculated using two-tailed paired t test (b–e). Exact p-values of the comparisons are displayed above the brackets and numbers in bold indicate statistical significance (p < 0.05). Source data are provided as a Source Data file.