Fig. 5: Alterations in fecal and blood metabolite levels. | Nature Communications

Fig. 5: Alterations in fecal and blood metabolite levels.

From: A legume-enriched diet improves metabolic health in prediabetes mediated through gut microbiome: a randomized controlled trial

Fig. 5

A Principal coordinate analysis of fecal and plasma metabolome based on Bray-Curtis distances. R2 values and p-values were calculated from the two-sided PERMANOVA test. All three time points share the same axes, showing the first two principal coordinates and labeled with the percent variance explained. B, C Heatmap of q-values and beta coefficients of fecal metabolites (B) and plasma metabolites (C) across the whole study period. *q (Time) < 0.05, **q (Time) < 0.01, and ***q (Time) < 0.001 denote p-adjusted values for the time coefficient from the LMM model (two-sided) performed seperately for each group. p-values were adjusted for multiple hypothesis testing using the Benjamini-Hochberg procedure. See Supplementary Data 1 for full names of metabolite abbreviations.

Back to article page