Table 1 Daily intake of energy and nutrients during dietary intervention. Data is presented as mean ± SEM

From: A legume-enriched diet improves metabolic health in prediabetes mediated through gut microbiome: a randomized controlled trial

 

Week 0

Week 4

Week 8

Week 12

Week 16

q-value (β coefficients)

Time

Treatment

Interaction

Energy Intake (kcal/d)

CG

1777.36 ± 64.34

1624.82 ± 47.83

1579.03 ± 38.29

1489.17 ± 37.44

1507.84 ± 35.60

2.49×10-13 (-0.05)

0.48 (-0.1)

0.38 (-0.01)

IG

1756.11 ± 39.83

1548.19 ± 41.54

1468.77 ± 38.80

1443.17 ± 34.72

1400.60 ± 31.62

Carbohydrate (g/d)

CG

222.40 ± 8.11

234.25 ± 6.45

230.32 ± 5.70

222.03 ± 5.73

224.82 ± 5.29

0.46 (-0.005)

0.1 5(-0.19)

0.03 (-0.03)

IG

223.15 ± 5.38

208.68 ± 5.24

201.62 ± 5.22

197.77 ± 4.60

196.35 ± 4.47

Protein (g/d)

CG

70.72 ± 2.74

72.45 ± 1.89

70.10 ± 1.40

66.23 ± 1.22

68.22 ± 1.21

8.03×10-3 (-0.02)

0.35 (-0.09)

0.21 (-0.01)

IG

68.76 ± 2.01

71.71 ± 1.72

68.35 ± 1.47

68.32 ± 1.56

67.91 ± 1.38

Fat (g/d)

CG

64.83 ± 3.42

43.10 ± 2.05

40.77 ± 1.65

36.08 ± 1.45

35.71 ± 1.35

2.52×10-30 (-0.08)

0.67 (0.05)

0.19 (0.01)

IG

63.60 ± 2.63

46.31 ± 1.92

42.29 ± 1.79

41.41 ± 1.62

37.65 ± 1.32

Saturated Fat (g/d)

CG

22.57 ± 1.17

15.17 ± 0.82

14.65 ± 0.70

12.64 ± 0.62

13.63 ± 0.64

3.99×10-21 (-0.07)

0.85 (0.03)

0.42 (0.008)

IG

21.98 ± 0.94

15.97 ± 0.84

14.97 ± 0.89

14.17 ± 0.73

13.70 ± 0.61

Dietary fiber (g/d)

CG

17.39 ± 0.85

16.83 ± 0.70

16.25 ± 0.53

14.89 ± 0.58

14.00 ± 0.58

1.07×10-4 (-0.02)

3.44×10-13 (0.70)

9.49×10-36 (0.10)

IG

18.62 ± 0.81

35.89 ± 0.73

36.26 ± 0.60

35.84 ± 0.70

35.44 ± 0.63

Sodium (mg/d)

CG

2478.50 ± 116.52

1807 ± 67.9

1909 ± 67.8

1604 ± 53.0

1632 ± 47.8

2.9×10-18 (-0.07)

0.18 (0.18)

0.84 (-0.002)

IG

2591 ± 96.5

2020 ± 89.1

1818 ± 71.6

1810 ± 68.1

1730 ± 56.5

  1. Analysis done using linear mixed effects model (two-sided) with week and treatment included as fixed factors, age and sex as covariates. q-values were adjusted for multiple hypothesis testing using the Benjamini-Hochberg procedure. Number of participants in IG over weeks: week 0, n = 63; week 4, n = 58; week 8, n = 57; week 12, n = 57; week 16, n = 57; number of participants in CG over weeks: week 0, n = 64; week 4, n = 60; week 8, n = 59; week 12, n = 59; week 16, n = 60. The numbers in brackets below the q-value are the corresponding β coefficients calculated from the scaled data. Bold values represent statistical significance with q < 0.05.
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