Table 1 CHD6 plasmid mutation summary

From: CHD6 has poly(ADP-ribose)- and DNA-binding domains and regulates PARP1/2-trapping inhibitor sensitivity via abasic site repair

GFP Mutant

Amino Acid Position(s)

Nucleotide position(s)

Codon Change

ΔPBD

K195-198 > A, K200 > A, R201 > A, K202 > A

583–594, 597–606

AAA > GCA, AAG > GCG, AGG > GCG

ΔCD

F318 > A, Y322 > A,

Y398 > A, W402 > A

952–954, 964–966,

1192–1194, 1204–1206

TTC > GCC, TAT > GCT,

TAC > GCC, TGG > GCG

ΔAT-Hook

R1182 > A, R1184 > A, K1188 > A

3544–3546, 3550–3552, 3562–3564

AGA > GCT, AGG > GCC, AAG > GCC

ΔSANT1

R1534 > A, R1537 > A

4600–4602, 4609–4611

CGT > GCA, AGA > GCT

ΔSANT2

R1534 > A, R1537 > A

4661–4663, 4670–4672

CGT > GCA, AGA > GCT

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