Fig. 4: Correlations of immunological and virological variables for the ATI participants (not NNRTI-containing regimen).

a Heat map of Spearman’s rank correlations between immunological and virological variables for the ATI participants (not NNRTI-containing regimen). *Asterisks noted at correlations with P values < 0.05. b Correlation between nadir CD4 + T cell count and CD4 + T cell count at ATI start (n = 206). c Correlation between nadir CD4 + T cell count and time to viremia of 50 (circles; n = 208), 400 (squares; n = 206) and 10,000 (triangles; n = 142) copies/mL. d–f Correlations between initial viral doubling time and time to viremia of 50 (d, circles; n = 357), 400 (e, squares; n = 357) and 10,000 (f, triangles; n = 261) copies/mL, respectively. P values were calculated using two-tailed Spearman’s correlation coefficient. ART antiretroviral therapy, ATI ART interruption, NNRTI non-nucleoside reverse transcriptase inhibitor.