Fig. 4: Evaluating data-driven RNA structure models with the area under the receiver operating characteristic curve (AUROC).
From: Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq
a Bar plot depicting AUROC values for DMS reactivities derived from five biological replicates of the t/PK domain (left, blue bar) and four biological replicates of the CR4/5 domain (right, green bar). Data are presented as means ± SD. b Receiver operating characteristic (ROC) curve comparing the t/PK Chen model with our DMS reactivities of the t/PK domain from four replicates (different colored lines). c ROC curve comparing the CR4/5 Chen model without DMS reactivities of the CR4/5 domain from four biological replicates (different colored lines). Source data are provided as a Source Data file.
