Fig. 2: Illustration of noise blow-up in RL-deconvolution of an image acquisition of mitochondria in BPAE cells.
From: Noise amplification and ill-convergence of Richardson-Lucy deconvolution
a–d Rows indicate the iteration number, starting from the raw image acquisition (iteration = 1). Columns show the mean (first column) and standard deviation (second column) over the \(M=10\) noise independent deconvolutions, the mean square (third column) and the variance (fourth column) of the FT of the \(M\) deconvolutions. The first two columns show a 251 × 251 pixel crop of the 960 × 960 pixel area on which the deconvolution is applied in order to make the smaller details more clear. The last two columns pertain to the full 960 × 960 pixel deconvolution. The diffraction limit at \(2{NA}/\lambda \) is indicated with red dashed circles. Scale bar (a–d) 4 μm.
