Table 2 Absolute risks (in %, incident/total patients) of individual and composite cardiovascular outcomes, stratified by SARS-CoV-2 status and CHD status

From: Cardiovascular post-acute sequelae of SARS-CoV-2 in children and adolescents: cohort study using electronic health records

 

SARS-CoV-2-positive

SARS-CoV-2-negative

 

CHD (N = 13,646)

Non-CHD (N = 284,274)

Overall (N = 297,920)

CHD (N = 46,962)

Non-CHD (N = 868,440)

Overall (N = 915,402)

Any cardiovascular outcome

5.566 (601/10,797)

2.19 (5895/269,210)

2.32 (6496/280,007)

3.998 (1529/38,248)

1.261 (10,481/831,098)

1.381 (12,010/869,346)

Hypertension

1.531 (195/12,736)

0.333 (936/281,427)

0.384 (1131/294,163)

1.08 (481/44,548)

0.209 (1801/861,469)

0.252 (2282/906,017)

Any arrhythmias

0.967 (126/13,029)

0.073 (208/283,655)

0.113 (334/296,684)

0.79 (355/44,955)

0.053 (461/866,011)

0.09 (816/910,966)

Atrial fibrillation

0.081 (11/13,619)

0.006 (16/284,233)

0.009 (27/297,852)

0.038 (18/46,896)

0.005 (46/868,329)

0.007 (64/915,225)

Ventricular arrhythmias

0.863 (113/13,089)

0.06 (171/283,757)

0.096 (284/296,846)

0.695 (314/45,159)

0.044 (378/866,270)

0.076 (692/911,429)

Atrial flutter

0.059 (8/13,577)

0.002 (7/284,243)

0.005 (15/297,820)

0.092 (43/46,754)

0.002 (17/868,365)

0.007 (60/915,119)

Premature atrial or ventricular contractions

0.059 (8/13,619)

0.009 (26/284,206)

0.011 (34/297,825)

0.058 (27/46,862)

0.006 (52/868,245)

0.009 (79/915,107)

Any inflammatory heart disease

0.125 (17/13,603)

0.044 (126/284,132)

0.048 (143/297,735)

0.094 (44/46,828)

0.015 (134/868,141)

0.019 (178/914,969)

Pericarditis

0.081 (11/13,628)

0.014 (39/284,198)

0.017 (50/297,826)

0.077 (36/46,886)

0.007 (64/868,296)

0.011 (100/915,182)

Myocarditis

0.059 (8/13,620)

0.034 (97/284,185)

0.035 (105/297,805)

0.019 (9/46,902)

0.01 (83/868,259)

0.01 (92/915,161)

Any other cardiac disorders

2.236 (281/12,565)

0.079 (225/283,615)

0.171 (506/296,180)

1.632 (710/43,513)

0.055 (474/866,289)

0.13 (1184/909,802)

Heart failure

1.609 (208/12,930)

0.02 (57/284,114)

0.089 (265/297,044)

1.179 (527/44,688)

0.012 (106/868,010)

0.069 (633/912,698)

Cardiomyopathy

0.578 (77/13,331)

0.042 (118/283,824)

0.066 (195/297,155)

0.361 (166/46,046)

0.028 (245/867069)

0.045 (411/913115)

Cardiac arrest

0.483 (65/13,461)

0.032 (91/284,122)

0.052 (156/297,583)

0.356 (165/46,303)

0.022 (194/867807)

0.039 (359/914110)

Cardiogenic shock

0.155 (21/13,526)

0.006 (17/284,233)

0.013 (38/297,759)

0.12 (56/46,554)

0.002 (18/868,332)

0.008 (74/914,886)

Any thrombotic disorders

0.913 (119/13,029)

0.102 (288/283,427)

0.137 (407/296,456)

0.737 (332/45,039)

0.084 (728/865,935)

0.116 (1060/910,974)

Pulmonary embolism

0.103 (14/13,618)

0.022 (62/284,178)

0.026 (76/297,796)

0.047 (22/46,872)

0.013 (110/868,175)

0.014 (132/915,047)

Deep vein thrombosis

0.096 (13/13,585)

0.011 (31/284,188)

0.015 (44/297,773)

0.062 (29/46,848)

0.01 (86/868,264)

0.013 (115/915,112)

Thrombophlebitis

0.096 (13/135,91)

0.018 (51/284,141)

0.021 (64/297,732)

0.036 (17/46,817)

0.017 (151/867,965)

0.018 (168/914,782)

Thromboembolism

0.896 (117/13,064)

0.091 (258/283,513)

0.126 (375/296,577)

0.72 (325/45,113)

0.074 (639/866,229)

0.106 (964/911,342)

Cardiovascular-related symptoms

2.002 (259/12,938)

1.748 (4772/272,941)

1.76 (5031/285,879)

1.028 (463/45,035)

0.959 (8071/842,021)

0.962 (8534/887,056)

Chest pain

1.345 (177/13,160)

1.229 (3401/276,688)

1.234 (3578/289,848)

0.637 (292/45,810)

0.611 (5202/851,857)

0.612 (5494/897,667)

Palpitations

0.564 (76/13,474)

0.378 (1067/282,181)

0.387 (1143/295,655)

0.274 (127/46,402)

0.181 (1566/863,436)

0.186 (1693/909,838)

Syncope

0.371 (50/13,482)

0.42 (1181/281,122)

0.418 (1231/294,604)

0.271 (126/46,454)

0.298 (2563/860,375)

0.297 (2689/906,829)