Table 2 Absolute risks (in %, incident/total patients) of individual and composite cardiovascular outcomes, stratified by SARS-CoV-2 status and CHD status
SARS-CoV-2-positive | SARS-CoV-2-negative | |||||
---|---|---|---|---|---|---|
CHD (N = 13,646) | Non-CHD (N = 284,274) | Overall (N = 297,920) | CHD (N = 46,962) | Non-CHD (N = 868,440) | Overall (N = 915,402) | |
Any cardiovascular outcome | 5.566 (601/10,797) | 2.19 (5895/269,210) | 2.32 (6496/280,007) | 3.998 (1529/38,248) | 1.261 (10,481/831,098) | 1.381 (12,010/869,346) |
Hypertension | 1.531 (195/12,736) | 0.333 (936/281,427) | 0.384 (1131/294,163) | 1.08 (481/44,548) | 0.209 (1801/861,469) | 0.252 (2282/906,017) |
Any arrhythmias | 0.967 (126/13,029) | 0.073 (208/283,655) | 0.113 (334/296,684) | 0.79 (355/44,955) | 0.053 (461/866,011) | 0.09 (816/910,966) |
Atrial fibrillation | 0.081 (11/13,619) | 0.006 (16/284,233) | 0.009 (27/297,852) | 0.038 (18/46,896) | 0.005 (46/868,329) | 0.007 (64/915,225) |
Ventricular arrhythmias | 0.863 (113/13,089) | 0.06 (171/283,757) | 0.096 (284/296,846) | 0.695 (314/45,159) | 0.044 (378/866,270) | 0.076 (692/911,429) |
Atrial flutter | 0.059 (8/13,577) | 0.002 (7/284,243) | 0.005 (15/297,820) | 0.092 (43/46,754) | 0.002 (17/868,365) | 0.007 (60/915,119) |
Premature atrial or ventricular contractions | 0.059 (8/13,619) | 0.009 (26/284,206) | 0.011 (34/297,825) | 0.058 (27/46,862) | 0.006 (52/868,245) | 0.009 (79/915,107) |
Any inflammatory heart disease | 0.125 (17/13,603) | 0.044 (126/284,132) | 0.048 (143/297,735) | 0.094 (44/46,828) | 0.015 (134/868,141) | 0.019 (178/914,969) |
Pericarditis | 0.081 (11/13,628) | 0.014 (39/284,198) | 0.017 (50/297,826) | 0.077 (36/46,886) | 0.007 (64/868,296) | 0.011 (100/915,182) |
Myocarditis | 0.059 (8/13,620) | 0.034 (97/284,185) | 0.035 (105/297,805) | 0.019 (9/46,902) | 0.01 (83/868,259) | 0.01 (92/915,161) |
Any other cardiac disorders | 2.236 (281/12,565) | 0.079 (225/283,615) | 0.171 (506/296,180) | 1.632 (710/43,513) | 0.055 (474/866,289) | 0.13 (1184/909,802) |
Heart failure | 1.609 (208/12,930) | 0.02 (57/284,114) | 0.089 (265/297,044) | 1.179 (527/44,688) | 0.012 (106/868,010) | 0.069 (633/912,698) |
Cardiomyopathy | 0.578 (77/13,331) | 0.042 (118/283,824) | 0.066 (195/297,155) | 0.361 (166/46,046) | 0.028 (245/867069) | 0.045 (411/913115) |
Cardiac arrest | 0.483 (65/13,461) | 0.032 (91/284,122) | 0.052 (156/297,583) | 0.356 (165/46,303) | 0.022 (194/867807) | 0.039 (359/914110) |
Cardiogenic shock | 0.155 (21/13,526) | 0.006 (17/284,233) | 0.013 (38/297,759) | 0.12 (56/46,554) | 0.002 (18/868,332) | 0.008 (74/914,886) |
Any thrombotic disorders | 0.913 (119/13,029) | 0.102 (288/283,427) | 0.137 (407/296,456) | 0.737 (332/45,039) | 0.084 (728/865,935) | 0.116 (1060/910,974) |
Pulmonary embolism | 0.103 (14/13,618) | 0.022 (62/284,178) | 0.026 (76/297,796) | 0.047 (22/46,872) | 0.013 (110/868,175) | 0.014 (132/915,047) |
Deep vein thrombosis | 0.096 (13/13,585) | 0.011 (31/284,188) | 0.015 (44/297,773) | 0.062 (29/46,848) | 0.01 (86/868,264) | 0.013 (115/915,112) |
Thrombophlebitis | 0.096 (13/135,91) | 0.018 (51/284,141) | 0.021 (64/297,732) | 0.036 (17/46,817) | 0.017 (151/867,965) | 0.018 (168/914,782) |
Thromboembolism | 0.896 (117/13,064) | 0.091 (258/283,513) | 0.126 (375/296,577) | 0.72 (325/45,113) | 0.074 (639/866,229) | 0.106 (964/911,342) |
Cardiovascular-related symptoms | 2.002 (259/12,938) | 1.748 (4772/272,941) | 1.76 (5031/285,879) | 1.028 (463/45,035) | 0.959 (8071/842,021) | 0.962 (8534/887,056) |
Chest pain | 1.345 (177/13,160) | 1.229 (3401/276,688) | 1.234 (3578/289,848) | 0.637 (292/45,810) | 0.611 (5202/851,857) | 0.612 (5494/897,667) |
Palpitations | 0.564 (76/13,474) | 0.378 (1067/282,181) | 0.387 (1143/295,655) | 0.274 (127/46,402) | 0.181 (1566/863,436) | 0.186 (1693/909,838) |
Syncope | 0.371 (50/13,482) | 0.42 (1181/281,122) | 0.418 (1231/294,604) | 0.271 (126/46,454) | 0.298 (2563/860,375) | 0.297 (2689/906,829) |