Fig. 2: ddPCR quantification of gene expression in EVs. | Nature Communications

Fig. 2: ddPCR quantification of gene expression in EVs.

From: Analysis of human urinary extracellular vesicles reveals disordered renal metabolism in myotonic dystrophy type 1

Fig. 2

a We used ddPCR to quantify expression of PCK1, HPD, DPYS, GSTA1, ACY1, ETFB, GCDH, HSD17B14, PIGT, BIN1, KRT20, and HPGD normalized to FAM168A in urinary EVs of DM1 (N = 39–47), DM2 (N = 10–13), DMD (N = 8–12), and UA controls (N = 27–39). ****P < 0.0001; ***P < 0.001; **P < 0.01; *P < 0.05 (one-way ANOVA/Tukey). b ddPCR quantification of PCK1, HPD, DPYS, GSTA1, ACY1, PIGT, BIN1, and HPGD expression normalized to FAM168A in serum EVs of DM1 (N = 4–8) and UA controls (N = 3–7). Error bars indicate ±s.e.m. Source data are provided as a Source Data file.

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