Fig. 9: Administration of Fu-Hp in mice leads to the upregulation of pro-inflammatory cytokine expression in vivo.
From: Fucosylated haptoglobin promotes inflammation via Mincle in sepsis: an observational study
a The concentrations of IL-1β, IL-6, and TNF were measured by ELISA in plasma of female 8-week-old C57BL/6 mice following Fu-Hp administration (n = 6 per group). Statistical significance was calculated with a Kruskal-Wallis test with Dunn’s test and presented as means ± SEM. ns, not significant. b The concentrations of IL-1β, IL-6, and TNF were measured by ELISA in indicated organ of female 8-week-old C57BL/6 mice following Fu-Hp administration (n = 6 per group). Statistical significance was calculated with a two-sided unpaired t-test with Mann-Whitney test and presented as means ± SEM. ns, not significant. c The relative expression of indicated genes in indicated organ of female 8-week-old C57BL/6 mice following Fu-Hp administration (n = 6 per group). Statistical significance was calculated with a two-way ANOVA with Bonferroni’s test and presented as means ± SEM.
