Table 1 Demographic and neuropsychological data

From: Dopaminergic modulation and dosage effects on brain state dynamics and working memory component processes in Parkinson’s disease

 

HC

PD

HC versus PD-OFF

PD-OFF versus PD-ON

  

PD-OFF

PD-ON

t-/chi-stats

p-value

t-/chi-stats

p-value

Sample size

37

27

N/A

N/A

Age (year)

71 ± 5

70 ± 6

1.01

0.28

N/A

Sex (F/M)

22F/15M

14F/13M

0.66

0.55

N/A

Education (years)

16 ± 2

17 ± 2

−1.11

0.27

N/A

Disease duration (year)

N/A

4.26 ± 3.59

N/A

N/A

 LEDD

N/A

550.72 ± 270.22

N/A

N/A

 GDS

1.02 ± 2.34

2.33 ± 1.69

−2.47

0.02

N/A

 MOCA

27.31 ± 2.18

26.78 ± 3.04

0.80

0.42

N/A

Maximum Disp (mm)

1.82 ± 1.47

1.41 ± 0.82

1.44 ± 0.58

1.30

0.20

0.70

0.84

 Maximum FD (mm)

0.77 ± 1.12

0.58 ± 0.44

0.51 ± 0.23

0.96

0.39

0.82

0.35

 MDS-UPDRS III

N/A

36.37 ± 12.47

23.78 ± 11.58

N/A

7.76

3.15e−8

 SDMT oral

53.3 ± 9.13

49.54 ± 8.49

48.63 ± 9.03

1.66

0.10

0.61

0.55

 SDM written

49.54 ± 11.1

45.19 ± 9.99

46.78 ± 11.9

1.59

0.12

−1.12

0.26

Sternberg LL ACC (%)

97 ± 3

98 ± 3

97 ± 4

−0.97

0.34

1.27

0.21

Sternberg HL ACC (%)

93 ± 4

95 ± 5

94 ± 5

−2.41

0.02

1.30

0.21

Sternberg DL ACC (%)

96 ± 6

95 ± 5

96 ± 5

0.37

0.72

−0.23

0.82

Sternberg LL RT (sec)

1.00 ± 0.24

1.01 ± 0.20

0.99 ± 0.23

−0.07

0.94

0.46

0.65

Sternberg HL RT (sec)

1.26 ± 0.24

1.25 ± 0.20

1.30 ± 0.30

0.18

0.86

−0.90

0.38

Sternberg DL RT (sec)

1.29 ± 0.26

1.29 ± 0.23

1.31 ± 0.35

−0.03

0.98

−0.53

0.59

  1. Table shows the mean ± standard deviation for HC and PD groups. p-values of HC versus PD-OFF are derived from two-sample t-tests. p-values of the PD-OFF and PD-ON are derived from paired-sample t-tests.
  2. HC healthy controls, PD-OFF Parkinson’s disease, off medication, PD-ON Parkinson’s disease, on medication, F female, M male, LEDD levodopa equivalent daily dosage (mg/day), GDS geriatric depression scale, Disp displacement, FD frame-wise displacement, MDS-UPDRS III movement disorders society-unified Parkinson’s disease scale motor score, SDMT Oral symbol digit modalities test, oral adjusted T score, SDMT Written symbol digit modalities test, written adjusted T score, LL low load, HL high load, DL distractor load, ACC accuracy, RT reaction time.
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