Table 1 Peak of clusters showing significant reduction in brain activation on amisulpride compared to placebo during reward outcome in whole brain analysis (FSL randomise: two-sided paired t-test comparing amisulpride to placebo, with 5000 permutations and FWE correction for multiple comparisons using threshold-free cluster enhancement at p < 0.05)
From: Striatal dopamine D2/D3 receptor regulation of human reward processing and behaviour
Cluster peak | Number of voxels | Cluster peak co-ordinates (MNI) | Cluster p-value (FWE corrected) | Z-MAX |
|---|---|---|---|---|
Frontal orbital cortex | 6843 | 46, 28, −8 | 0.018 | 3.54 |
Right caudate | 98 | 8,8, 10 | 0.045 | 3.54 |
Inferior frontal gyrus, pars triangularis | 21 | −54,26, 6 | 0.046 | 3.54 |
