Table 2 Peak of clusters showing significantly greater reduction in neural response on amisulpride relative to placebo compared to aripiprazole relative to placebo during reward outcome in whole brain analysis (FSL randomise: two-sided independent sample t-tests comparing amisulpride–placebo to aripiprazole–placebo, with 5000 permutations and FWE correction for multiple comparisons using threshold-free cluster enhancement at p < 0.05)
From: Striatal dopamine D2/D3 receptor regulation of human reward processing and behaviour
Cluster peak | Number of voxels | Cluster peak co-ordinates (MNI) | Cluster p-value (FWE corrected) | Z-MAX |
---|---|---|---|---|
Frontal operculum cortex | 928 | 44, 18, 8 | 0.040 | 3.54 |
Right caudate | 59 | 10, 2, 14 | 0.044 | 3.54 |
Central opercular cortex | 26 | 46, -8, 6 | 0.048 | 3.09 |