Fig. 4: The OSPPB hydrogel inhibits angiogenesis and neurogenesis. | Nature Communications

Fig. 4: The OSPPB hydrogel inhibits angiogenesis and neurogenesis.

From: Neurovascularization inhibiting dual responsive hydrogel for alleviating the progression of osteoarthritis

Fig. 4

a, b Representative microscopy images of EPCs and TG cells showing cell migration, tube formation, and morphology after 24 h of treatment. Scale bars = 100 μm. c, d Quantification of migrated cells and the migration distance of EPCs after treatment. n = 6, F(6, 35) = 45.9, p < 0.0001 in (c). n = 6, F(6, 35) = 89.54, p < 0.0001 in (d). e, f Quantification of the interactions and dendritic length of TG cells after treatment. n = 6, F(6, 35) = 39.66, p < 0.0001 in (e). n = 6, F(6, 35) = 85.86, p < 0.0001 in (f). Data are shown as the means and standard deviations. One-way ANOVA is followed by the Tukey-Kramer method for post hoc multiple comparisons.

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