Fig. 1: Transcriptomic- and proteomic-based clustering reveals only two distinct fiber types. | Nature Communications

Fig. 1: Transcriptomic- and proteomic-based clustering reveals only two distinct fiber types.

From: Human skeletal muscle fiber heterogeneity beyond myosin heavy chains

Fig. 1

A Transcriptomic and proteomic workflow (created using BioRender.com). B–D Dynamic range curves for MYH7, MYH2, and MYH1, with calculated assignment thresholds for fiber typing. E, F Distribution of fibers by expression of MYHs in transcriptomics and proteomics datasets. G, H Uniform manifold approximation and projection (UMAP) plots for transcriptomics and proteomics, colored by MYH-based fiber type. I, J Feature plots displaying the expression of MYH7, MYH2, and MYH1 in transcriptomics and proteomics.

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