Fig. 1: snRNA-seq identifies tarsal plate and MG cell subpopulations.
From: Identification of Meibomian gland stem cell populations and mechanisms of aging
a UMAP plot of snRNA-seq data from pooled tarsal plate samples from four 8-week-old and four 21-month-old male C57BL/6 J mice, respectively, with two replicates for each age. b Schematic diagram of MG structure indicating the spatial locations of MG subpopulations and the stromal environment. c, d RNA Velocity (c) and pseudotime analyses (d) predictions of the differentiation trajectories of MG cellular subpopulations. RNA Velocity (c) predicts that ductular cells can differentiate towards either duct or acinus. See also Supplementary Fig. S1.
