Fig. 4: Performance of proteins measured using Olink and SomaScan platforms for prediction of incident IHD. | Nature Communications

Fig. 4: Performance of proteins measured using Olink and SomaScan platforms for prediction of incident IHD.

From: Comparative studies of 2168 plasma proteins measured by two affinity-based platforms in 4000 Chinese adults

Fig. 4

Analyses were conducted for 1694 matched proteins among 3976 participants, including 1951 IHD cases and 2025 subcohort participants. Conventional risk factors for cardiovascular disease included age, sex, smoking, type 2 diabetes, systolic blood pressure, and waist circumference. Protein measurements for 1694 one-to-one matched proteins from both platforms or from one platform were used to build the models. Data are presented as estimated C-statistics, with error bars indicating 95% confidence intervals. NRI were computed with a decile-based method. IHD ischaemic heart disease, NRI net reclassification index.

Back to article page