Fig. 2: The characterization of CP@MSN/PB@CWL (CMPBC).
From: Bioactive nanomotor enabling efficient intestinal barrier penetration for colorectal cancer therapy
a A schematic of the synthetic procedure of CMPBC. b TEM images of PDA, MSN, MSN/PDA, and negative staining TEM images of CWL and CMPBC. The experiment was repeated independently with similar results. c Element mapping image of MSN/PDA. d Schematic diagram of the recognition of nanomotor to IgA-labeled magnetic beads. e The fluorescence intensity of magnetic beads following their incubation with various nanoparticles (n = 3 independent experiments). f NO release rate of different nanoparticles in simulated artificial colon fluid (n = 3 independent experiments). g Schematic diagram of the MPBC movement direction under NIR (808 nm) irradiation. Motion speed (h) and MSD (i) of different nanoparticles in mucin solution (n = 3 independent experiments). Data are presented in the form of mean values ± standard deviation (SD). Significance was assessed via one-way analysis of variance (ANOVA) with Tukey’s post hoc test. Source data are provided as a Source Data file.
