Fig. 7: Changes in collagen fiber in the dermis development.
From: Keratinocyte-driven dermal collagen formation in the axolotl skin
a, b Ultrastructure of 12 cm dermis. a Keratinocyte and collagen fibers in the stratum baladachinum. b Collagen fibers in the stratum compactum. c, d Ultrastructure of 5 cm dermis. c Keratinocyte and collagen fibers in the stratum coniunctum. d Epidermis side of the stratum coniunctum. e Analysis of the size of collagen fibrils (n = 3 biologically independent samples). Each point on the box plot represents all measured data points. p values: 2.83 e−99. The statistical analysis was performed using t-tests (two-tailed). ***p < 0.01. The representative images were selected from 15 images made from three independent samples. The scale bars in (a–d) are 1 μm. Each box represents the interquartile range (IQR, the range between the 25th and 75th percentile) with the mid-point of the data, bars indicate the upper and lower value within 1.5 times the IQR. Source data are provided as a Source Data file.
