Fig. 1: The interactions between different microgrooves and cells.
From: Drop-shaped microgrooves guide unidirectional cell migration for enhanced endothelialization
a Schematic diagram of parallel microgrooves and their influence on cell migration. b Schematic diagram of drop-shaped microgrooves and their influence on cell migration. c Scanning electron microscope (SEM) images of the flat surface, parallel microgrooves, and drop-shaped grooves. Scale bars, 50 μm. d Confocal microscopy images of cells spreading on different surfaces. Scale bar, 100 μm. Statistics of cells orientation degree (e), cell spreading area (f) (n = 16 cells from three technical replicates), nuclear area (g) (n = 16 cells from three technical replicates), and cell circularity (h) (n = 16 cells from three technical replicates) on different surfaces. Data are presented as means ± standard deviation (SD). Significance determined by unpaired two-tailed t-test (f–h).
