Fig. 4: Structural insights into binding mode of Yck2 inhibitors with GW. | Nature Communications

Fig. 4: Structural insights into binding mode of Yck2 inhibitors with GW.

From: Structure-guided optimization of small molecules targeting Yck2 as a strategy to combat Candida albicans

Fig. 4

Structure of the Yck2:GW (black), Yck2:1e (light blue), Yck2:1f (dark blue), Yck2:2a (pink), and Yck2:2b (red) complexes. Protein shown in cartoon representation, and molecules shown in ball-and-stick. Key residues as well as the 6-C position of the core heterocycle of the compounds, are marked with text.

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