Fig. 3: H2S-activated decomposition performances of CAA-PEG NSs in vitro.
From: In situ valence-transited arsenic nanosheets for multi-modal therapy of colorectal cancer
a The mimetic H2S-activated decomposition of CAA-PEG NSs at different time intervals. b Arsenic release from different release medium (pH 7.4, pH 6.2, and pH 7.4 + 3 mM NaHS) (Data are presented as mean values +/− SD, n = 3 independent experiments). c Arsenic release from release medium with escalating NaHS concentrations (Data are presented as mean values +/− SD, n = 3 independent experiments). d The XPS spectra of AsIII and AsV. e Valence transition efficiency of AsV to AsIII of CAA-PEG NSs in different concentrations of NaHS solution. f XRD and SAED pattern of ultrasmall CuS nanoparticles. g UV–vis absorption intensity and color changes (inserted) of CAA-PEG NSs at 1064 nm in different concentrations of NaHS solutions (Data are presented as mean values +/− SD, n = 3 independent experiments). h Photoacoustic signal intensity of CAA-PEG NSs with various concentrations of NaHS and the corresponding photoacoustic images (inserted) (Data are presented as mean values +/− SD, n = 3 independent experiments). The heating curve (i) and photothermal images (j) of CAA-PEG NSs under 1064 nm laser irradiation with different concentrations of NaHS solution (Data are presented as mean values +/− SD, n = 3 independent experiments). k Temperature variations of the mixture of aqueous CAA-PEG NSs solutions and NaHS under 1064 nm irradiation for seven light on/off cycles. For (c, i) One-way ANOVA with Dunnett’s Multiple Comparison Test was used to compare each group with the Control groups. P values were presented in absolute value in the figures.
