Fig. 4: De novo non-allelic gene conversion in a trio.
From: Genome-wide profiling of highly similar paralogous genes using HiFi sequencing
a Haplotypes are labeled in different colors in the proband, father, and mother, with matching colors indicating inherited haplotypes (haplotypes not inherited are labeled in gray in the parents). The black arrow denotes the SNV created by non-allelic gene conversion on haplotype 2 (labeled in red) of the proband. It is not present on the inherited haplotype, haplotype 2 (labeled in red) in the father. Instead, it is present on haplotype 4 (labeled in magenta) of the father, which belongs to the other gene in the paralog group. The curved arrow shows the direction of the gene conversion. b Close view of the converted variant.
