Fig. 5: Proteomic analysis of bone regeneration.

a GO terms with respect to biological process, cellular component and molecular function, and b KEGG pathway enrichment analyses. X-axis represents level of statistical significance of enrichment (Fisher exact test). c Volcano plot representation of differential abundance of protein. The x-axis indicates the differential expression profiles, plotting the log2(FC). The y-axis indicates p-values by unpaired two-tailed t-test. d heatmap of differentially expressed proteins. (n = 3) e Selected protein levels measured with Western blot at the middle (mid) and side of the implants (n = 4). Exact p-values are available in the Source Data file.