Fig. 6: Bone tissue strain analysis and compressive properties of bone implants. | Nature Communications

Fig. 6: Bone tissue strain analysis and compressive properties of bone implants.

From: A metamaterial scaffold beyond modulus limits: enhanced osteogenesis and angiogenesis of critical bone defects

Fig. 6

a 3D finite element model (FEM) of the 6-mm ulnar defect with implantation of CS or TMS and augmented with a plate. b FEM analysis of maximum principal strains within the soft callus tissue and scaffolds under different body weight (BW) loading in the ROI. c FEM maximum principal strain values under varying load conditions with randomly selected grids, n = 100, whiskers extend to the 10–90% values, box represents the 25th to 75th percentiles, and centre represents mean value. d FEM maximum principal strain values of different bone tissues under 1 BW with randomly selected grids, n = 25, whiskers extend to the 10-90% values, box represents the 25th to 75th percentiles and centre represents mean value. e Compressive properties of different metamaterials and bone implants. The plot is setup with strength normalized by the effective modulus vs. the effective modulus. The unattainable limit for one-stage metamaterial was plotted according to reference40. Commercial bulk metals for bone implants, including Ti alloys41, CoCr alloys42, and biodegradable Zn alloys43 are presented in solid squares. Bone scaffolds, including Ti6Al4V20, Ti44, biodegradable Zn11 and polyetheretherketone (PEEK)45 are labeled by circles with half-down interiors. Metamaterials, including metal46, polymer47, ceramics48, and carbon49 are labeled by diamonds with half-up interior.

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