Fig. 5: Correlations between immune module expression in the upper respiratory tract and peripheral blood of SARS-CoV-2-infected children and adolescents.
From: Age-associated differences in mucosal and systemic host responses to SARS-CoV-2 infection
Single-sample gene set enrichment analysis was used to calculate enrichment scores for gene modules in paired upper respiratory and peripheral blood samples from SARS-CoV-2-infected children and adolescents. Pearson’s correlation coefficients were then calculated to evaluate for linear relationships between expression of these modules in the upper respiratory tract and peripheral blood of the same individual. Positive correlations are displayed in purple and negative correlations are displayed in orange. The size and color of each circle correspond to the strength of the correlation; only statistically significant correlations after adjustment for multiple comparisons (padj < 0.05) are shown. Source data are provided as a source data file. (NK, natural killer).
