Table 1 Characteristics of the study population
From: Age-associated differences in mucosal and systemic host responses to SARS-CoV-2 infection
Young children (0–5 yr, n = 39) | School-age children (6–13 yr, n = 65) | Adolescents (14–20 yr, n = 56) | Adults (≥21 yr, n = 42) | p | |
|---|---|---|---|---|---|
Participant characteristics | |||||
Median [IQR] age, years | 3.0 [1.6, 4.9] | 10.1 [8.4, 12.1] | 17.1 [15.6, 18.5] | 46.2 [40.1, 53.8] | <0.0001 |
Female sex | 25 (64%) | 32 (49%) | 30 (54%) | 21 (50%) | 0.48 |
Obesitya | 7 (27%) | 18 (28%) | 18 (32%) | 6 (20%) | 0.69 |
Other comorbidities | 3 (8%) | 14 (22%) | 10 (18%) | 17 (45%) | 0.001 |
SARS-CoV-2 infection status | 0.66 | ||||
SARS-CoV-2-infected | 29 (74%) | 43 (66%) | 39 (70%) | 26 (62%) | |
SARS-CoV-2-uninfected (healthy) | 10 (26%) | 22 (34%) | 17 (30%) | 16 (38%) | |
SARS-CoV-2 illness characteristics | |||||
Asymptomatic | 14 (48%) | 20 (47%) | 14 (36%) | 2 (8%) | 0.002 |
Fever | 13 (45%) | 16 (37%) | 16 (41%) | 14 (54%) | 0.59 |
Cough | 7 (24%) | 10 (23%) | 19 (49%) | 19 (73%) | <0.0001 |
Headache | 3 (10%) | 8 (19%) | 19 (49%) | 15 (58%) | <0.0001 |
Abdominal pain | 2 (7%) | 4 (9%) | 4 (10%) | 8 (31%) | 0.06 |
Myalgias | 0 (0%) | 9 (21%) | 13 (33%) | 15 (58%) | <0.0001 |
Nasal congestion | 2 (7%) | 3 (7%) | 8 (21%) | 17 (65%) | <0.0001 |
Rhinorrhea | 4 (14%) | 1 (2%) | 8 (21%) | 14 (54%) | <0.0001 |
Loss of smell | 0 (0%) | 4 (9%) | 10 (26%) | 19 (73%) | <0.0001 |
Loss taste | 0 (0%) | 3 (7%) | 10 (26%) | 15 (58%) | <0.0001 |
Median [IQR] nasopharyngeal viral load, log10 copies/mL | 5.8 [4.0, 7.1] | 5.1 [3.5, 7.0] | 5.1 [3.7, 6.8] | 5.7 [4.6, 6.8] | 0.37 |
