Fig. 4: Two example cases of pre and postsynaptic ratio calculation.
From: Neurotransmitters’ white matter mapping unveils the neurochemical fingerprints of stroke
Top row – Lesion mask of two left hemisphere stroke lesions. Middle row – Percentage of each neurotransmitter system disrupted by the lesion, according to the receptor and transporter location density (location maps injury) and white matter projections (tract maps injury). Bottom row – Synaptic ratios presented in a natural logarithmic scale. 5HT1aR serotonin receptor 1a, 5HT1bR serotonin receptor 1b, 5HT2aR serotonin receptor 2a, 5HT4R serotonin receptor 4, 5HT6R serotonin receptor 6 5HTT serotonin transporter, alpha4beta2R acetylcholine receptor alpha4beta2, D1R dopamine receptor 1, D2R dopamine receptor 2, DAT dopamine transporter, M1R muscarinic 1 receptor, NAT noradrenaline transporter, VAChT acetylcholine vesicular transporter. Source data are provided as a Source Data file.
